Southampton U23
| Anglia - Premier League 2 | 03/06 19:00 | 1 |
[8] Southampton U23
v
Chelsea U23
[5] 
|
D | 0-0 | |
| Anglia - Premier League Cup U23 | 02/28 14:04 | - |
Newcastle U23
v
Southampton U23
|
L | 2-0 | |
| Anglia - Premier League 2 | 02/20 19:00 | 1 |
[1] Everton U23
v
Southampton U23
[7]
|
L | 2-0 | |
| Anglia - Premier League Cup U23 | 02/16 15:03 | - |
Bristol City U23
v
Southampton U23
|
W | 0-2 | |
| Anglia - Premier League Cup U23 | 02/13 20:53 | - |
Southampton U23
v
Swansea U23
|
L | 0-1 | |
| Anglia - Premier League 2 | 02/06 19:00 | 1 |
[11] Leicester U23
v
Southampton U23
[9]
|
W | 0-2 | |
| Anglia - Premier League 2 | 01/30 19:00 | 1 |
[10] Tottenham U23
v
Southampton U23
[8]
|
L | 3-1 | |
| Anglia - Premier League 2 | 01/16 19:00 | 1 |
[7] Southampton U23
v
Arsenal U23
[5] 
|
L | 1-3 | |
| Anglia - Premier League 2 | 01/06 13:00 | 1 |
[11] Reading U23
v
Southampton U23
[7]
|
L | 4-2 | |
| Anglia - EFL Trophy | 12/21 19:00 | 8 |
[1] Southampton U23
v
Reading U23
[2]
|
L | 4-5 | |
| Anglia - Premier League 2 | 12/09 12:00 | 1 |
[7] Southampton U23
v
Sunderland U23
[5] 
|
L | 0-2 | |
| Anglia - Premier League Cup U23 | 12/02 15:01 | - |
Southampton U23
v
Newcastle U23
|
W | 3-0 | |
| Anglia - Premier League 2 | 11/28 19:00 | 1 |
[6] Southampton U23
v
Everton U23
[1]
|
D | 1-1 | |
| Anglia - Premier League 2 | 11/21 14:05 | 1 |
[9] Chelsea U23
v
Southampton U23
[4]
|
L | 3-2 | |
| Anglia - EFL Trophy | 11/09 19:45 | 3 |
[2] Southampton U23
v
Crawley Town
[1] 
|
W | 4-0 | |
| Anglia - Premier League Cup U23 | 11/04 19:00 | - |
Swansea U23
v
Southampton U23
|
W | 0-1 | |
| Anglia - Premier League 2 | 10/31 19:00 | 1 |
[12] Derby U23
v
Southampton U23
[4]
|
L | 2-0 | |
| Anglia - Premier League 2 | 10/24 18:00 | 1 |
[2] Southampton U23
v
Man City U23
[4] 
|
L | 0-3 | |
| Anglia - Premier League 2 | 10/14 18:00 | 1 |
[10] Arsenal U23
v
Southampton U23
[2]
|
D | 0-0 | |
| Anglia - EFL Trophy | 10/04 18:45 | 2 |
[4] Colchester
v
Southampton U23
[3]
|
W | 1-2 | |
| Anglia - Premier League Cup U23 | 09/30 17:55 | - |
Southampton U23
v
Bristol City U23
|
L | 1-2 | |
| Anglia - Premier League 2 | 09/23 18:00 | 1 |
Southampton U23
v
Tottenham U23
|
W | 1-0 | |
| Anglia - Premier League 2 | 09/12 18:00 | 1 |
Southampton U23
v
Reading U23
|
W | 3-1 | |
| Anglia - EFL Trophy | 08/30 19:47 | - |
Charlton
v
Southampton U23
|
D | 0-0 | |
| Anglia - Premier League 2 | 08/28 12:00 | 1 |
Sunderland U23
v
Southampton U23
|
L | 3-0 | |
| Anglia - Premier League Cup U21 | 04/20 18:00 | 1 |
Southampton U23
v
Blackburn U21
|
W | 2-1 | |
| Anglia - Premier League Cup U21 | 04/13 18:00 | 1 |
Blackburn U21
v
Southampton U23
|
D | 0-0 | |
| Anglia - Premier League Cup U21 | 03/05 19:00 | 2 |
Southampton U23
v
Derby - Rezerve
|
W | 4-2 | |
| Anglia - Premier League Cup U21 | 02/12 19:00 | 3 |
Southampton U23
v
Watford U23
|
W | 3-2 |
Echipa de fotbal Southampton U23 din Marea Britanie este o echipă de rezervă a clubului Southampton FC. Echipa evoluează în Premier League 2 Division 1, al doilea nivel al sistemului de fotbal pentru rezerve din Anglia. Southampton U23 și-a disputat meciurile de pe teren propriu pe stadionul Staplewood Campus din 2013 până în 2021, când s-a mutat pe stadionul St Mary's. Southampton U23 a câștigat o singură dată Premier League 2 Division 1, în sezonul 2016-2017. Echipa a mai câștigat și Premier League Cup de două ori, în sezoanele 2014-2015 și 2017-2018.